Farrin Abbott, SLAC/Flickr // CC BY-NC-SA 2.0
Farrin Abbott, SLAC/Flickr // CC BY-NC-SA 2.0

An Ancient Book Blasted with High-Powered X-Rays Reveals Text Erased Centuries Ago

Farrin Abbott, SLAC/Flickr // CC BY-NC-SA 2.0
Farrin Abbott, SLAC/Flickr // CC BY-NC-SA 2.0

A book of 10th-century psalms recovered from St. Catherine’s Monastery on Egypt's Sinai Peninsula is an impressive artifact in itself. But the scientists studying this text at the U.S. Department of Energy's SLAC National Accelerator Laboratory at Stanford University were less interested in the surface text than in what was hidden beneath it. As Gizmodo reports, the researchers were able to identify the remains of an ancient Greek medical text on the parchment using high-powered x-rays.

Unlike the Large Hadron Collider in Switzerland, the Stanford Synchrotron Radiation Lightsource (SSRL) used by the scientists is a much simpler and more common type of particle accelerator. In the SSRL, electrons accelerate to just below the speed of light while tracing a many-sided polygon. Using magnets to manipulate the electrons' path, the researchers can produce x-ray beams powerful enough to reveal the hidden histories of ancient documents.

Scanning an ancient text.
Mike Toth, R.B. Toth Associates, Flickr // CC BY-NC-SA 2.0

In the case of the 10th-century psalms, the team discovered that the same pages had held an entirely different text written five centuries earlier. The writing was a transcription of the words of the prominent Greek physician Galen, who lived from 130 CE to around 210 CE. His words were recorded on the pages in the ancient Syriac language by an unknown writer a few hundred years after Galen's death.

Several centuries after those words were transcribed, the ink was scraped off by someone else to make room for the psalms. The original text is no longer visible to the naked eye, but by blasting the parchment with x-rays, the scientists can see where the older writing had once marked the page. You can see it below—it's the writing in green.

X-ray scan of ancient text.
University of Manchester, SLAC National Accelerator Laboratory, Flickr // CC BY-NC-SA 2.0

Now that the researchers know the hidden text is there, their next step will be uncovering as many words as possible. They plan to do this by scanning the book in its entirety, a process that will take 10 hours for each of the 26 pages. Once they've been scanned and studied, the digital files will be shared online.

Particle accelerators are just one tool scientists use to decipher messages that were erased centuries ago. Recently, conservationists at the Library of Congress used multispectral imaging, a method that bounces different wavelengths of light off a page, to reveal the pigments of an old Alexander Hamilton letter someone had scrubbed out.

[h/t Gizmodo]

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Medicine
Charles Dickens Museum Highlights the Author's Contributions to Science and Medicine

Charles Dickens is celebrated for his verbose prose and memorable opening lines, but lesser known are his contributions to science—particularly the field of medicine.

A new exhibition at London’s Charles Dickens Museum—titled "Charles Dickens: Man of Science"—is showcasing the English author’s scientific side. In several instances, the writer's detailed descriptions of medical conditions predated and sometimes even inspired the discovery of several diseases, The Guardian reports.

In his novel Dombey and Son, the character of Mrs. Skewton was paralyzed on her right side and unable to speak. Dickens was the first person to document this inexplicable condition, and a scientist later discovered that one side of the brain was largely responsible for speech production. "Fat boy" Joe, a character in The Pickwick Papers who snored loudly while sleeping, later lent his namesake to Pickwickian Syndrome, otherwise known as obesity hypoventilation syndrome.

A figurine of Fat Boy Joe
Courtesy of the Charles Dickens Museum

Dickens also wrote eloquently about the symptoms of tuberculosis and dyslexia, and some of his passages were used to teach diagnosis to students of medicine.

“Dickens is an unbelievably acute observer of human behaviors,” museum curator Frankie Kubicki told The Guardian. “He captures these behaviors so perfectly that his descriptions can be used to build relationships between symptoms and disease.”

Dickens was also chummy with some of the leading scientists of his day, including Michael Faraday, Charles Darwin, and chemist Jane Marcet, and the exhibition showcases some of the writer's correspondence with these notable figures. Beyond medicine, Dickens also contributed to the fields of chemistry, geology, and environmental science.

Less scientifically sound was the author’s affinity for mesmerism, a form of hypnotism introduced in the 1770s as a method of controlling “animal magnetism,” a magnetic fluid which proponents of the practice believed flowed through all people. Dickens studied the methods of mesmerism and was so convinced by his powers that he later wrote, “I have the perfect conviction that I could magnetize a frying-pan.” A playbill of Animal Magnetism, an 1857 production that Dickens starred in, is also part of the exhibit.

A play script from Animal Magnetism
Courtesy of the Charles Dickens Museum

Located at 48-49 Doughty Street in London, the exhibition will be on display until November 11, 2018.

[h/t The Guardian]

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Health
Feeling Down? Lifting Weights Can Lift Your Mood, Too
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There’s plenty of research that suggests that exercise can be an effective treatment for depression. In some cases of depression, in fact—particularly less-severe ones—scientists have found that exercise can be as effective as antidepressants, which don’t work for everyone and can come with some annoying side effects. Previous studies have largely concentrated on aerobic exercise, like running, but new research shows that weight lifting can be a useful depression treatment, too.

The study in JAMA Psychiatry, led by sports scientists at the University of Limerick in Ireland, examined the results of 33 previous clinical trials that analyzed a total of 1877 participants. It found that resistance training—lifting weights, using resistance bands, doing push ups, and any other exercises targeted at strengthening muscles rather than increasing heart rate—significantly reduced symptoms of depression.

This held true regardless of how healthy people were overall, how much of the exercises they were assigned to do, or how much stronger they got as a result. While the effect wasn’t as strong in blinded trials—where the assessors don’t know who is in the control group and who isn’t, as is the case in higher-quality studies—it was still notable. According to first author Brett Gordon, these trials showed a medium effect, while others showed a large effect, but both were statistically significant.

The studies in the paper all looked at the effects of these training regimes on people with mild to moderate depression, and the results might not translate to people with severe depression. Unfortunately, many of the studies analyzed didn’t include information on whether or not the patients were taking antidepressants, so the researchers weren’t able to determine what role medications might play in this. However, Gordon tells Mental Floss in an email that “the available evidence supports that [resistance training] may be an effective alternative and/or adjuvant therapy for depressive symptoms that could be prescribed on its own and/or in conjunction with other depression treatments,” like therapy or medication.

There haven’t been a lot of studies yet comparing whether aerobic exercise or resistance training might be better at alleviating depressive symptoms, and future research might tackle that question. Even if one does turn out to be better than the other, though, it seems that just getting to the gym can make a big difference.

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