Scientists at UC San Diego Want You to Mail Them Your Poop

iStock.com/mapichai
iStock.com/mapichai

Poop. It’s fun to say, funny to talk about, and makes for an all-purpose emoji. But who wants to actually handle it?

Now, researchers of the American Gut Project at the University of California, San Diego, may be giving people new motivations to not only retain a stool sample, but pack it up and ship it to them. According to Inside Science, a team led by biologist Rob Knight is currently welcoming fecal samples from the public at large to analyze their microbiome profiles.

The microbiome is the assembly of bacteria, fungi, and other organisms that live in and on our bodies, which can change in response to lifestyle habits like diet and exercise. Recent research suggests that some microbiome profiles may make people predisposed to conditions like obesity and cancer, and might even influence our mental health. Altering the microbiome may have potentially beneficial health effects, which is why researchers like Knight are looking to collect data—in this case, poop.

“Your microbiome weighs about as much as your brain does—you're talking about a couple of pounds of material,” Knight told Inside Science. “And it certainly has more cells, way more genes, arguably as much complexity as your brain. And we're just starting to understand the far-reaching effects that it has on the rest of your body.”

Knight says that over 10,000 people have already donated their excrement for science as part of the project. And it's already producing results. In the first published study of the American Gut Project's work, which appeared in the American Society for Microbiology's journal mSystems in May 2018, the researchers found that plant-heavy diets led to a more diverse bacterial colony in stomachs than people who ate comparatively fewer types of greens. Their data also showed some preliminary evidence that people with mental health complaints tended to have similar microbiomes as people who reported the same issues.

Knight and his colleagues would love to analyze your poop in an effort to compile more information, but there is a catch: Donors have to pay a $99 fee to join the project, an informal kind of crowdfunding that keeps the research financed. If you submit a sample—basically a poop swab taken from your used toilet tissue—the team at Human Gut will send you a personalized microbiome profile and an assessment of how your gut flora compares with the rest of the population. For incrementally larger fees, you might be able to see how your diet, level of exercise, and family members' flora affect your microbiome at finer resolutions. They’ll even test your dog’s donations.

You can join the effort here. The future of poop research thanks you for your participation.

[h/t SF Gate]

These ASMR-Ready Headphones Promise to Lull You to Sleep

AcousticSheep
AcousticSheep

What do hushed whispers, gently tapping fingernails, and Bob Ross’s voice have in common? They’re all examples of triggers that may cause what’s known as an autonomous sensory meridian response (ASMR), or, as Dictionary.com succinctly explains it, a “calming, pleasurable feeling often accompanied by a tingling sensation” that can be triggered by soothing stimuli. ASMR has recently been recognized as an effective relaxation technique for those looking to calm their nerves; now, ASMR enthusiasts and novices alike can experience it in the form of a sleep-ready headband.

Upon first glance, SleepPhones: ASMR Edition may look like just a fabric headband, but the device actually features flat speakers tucked into soft, stretchy, eco-friendly material. Unlike regular headphones, SleepPhones can be worn comfortably to bed, even if you sleep on your side, and they come preloaded with content designed to help you relax. They feature eight hours of built-in ASMR content by 16 different ASMR artists (or ASMRtists), including but not limited to tracks with rhythmic tapping and "peaceful Italian whisperings."

A close-up of the SleepPhones speaker technology
AcousticSheep

The speaker components of SleepPhones
AcousticSheep

Using SleepPhones is designed to be a stress-free experience. The speakers have the ability to play for 20 ad-free hours with a mere three-hour charging time in between. There are also zero cords involved, meaning you won’t get all tangled up as you lie down or if you have a tendency to toss and turn at night. The small button located in the back of the headband allows you to start, pause, or skip tracks and control the volume.

For people looking for ways to relax beyond yoga and meditation, ASMR may be the way to go. One study observed that subjects watching ASMR videos not only reported feeling that aforementioned pleasant tingling, but were also found to have reduced heart rates.

You can get a pair of your own SleepPhones on Kickstarter with a pledge of $75 or more. They come in three different sizes with seven colors from which to choose.

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FDA Is Warning Against Fecal Transplants After Person Dies From E. Coli Infection

iStock/artisteer
iStock/artisteer

Though it may sound gross, the benefits of a fecal transplant—taking the feces of one person and introducing it into the gastrointestinal tract of another—are promising for those suffering from a Clostridioides difficile infection. The tenacious infections are often the result of sustained antibiotic use, which can kill the patient's "good" gut bacteria and allow C. difficile to proliferate. As the theory goes, the “good” bacteria in feces transplanted from a healthy person may restore the infected person's microbiome and alleviate symptoms like life-threatening diarrhea.

The treatment, which is not FDA-approved, is risky. The FDA has announced that two people involved in a clinical trial recently received fecal transplants that contained drug-resistant bacteria, with one of them dying as a result.

According to The New York Times, the FDA did not offer details of either case, relating only that both patients were immunocompromised, which is one of the contraindications of receiving the transplant. The stool they received was believed to contain antibiotic-resistant E. coli bacteria.

As a result, the FDA is suspending a number of fecal transplant clinical trials until it can be determined how stool is being tested for contamination with potentially deadly bacteria and why the E. coli was not detected. The stool that infected both patients came from the same donor.

Fecal transplants are considered an experimental treatment for C. difficile infection when first-line treatment like antibiotics are ineffective. The fecal transplant is usually introduced to the digestive tract via pills or an infusion.

[h/t The New York Times]

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