Robin Stott, via Flickr // CC BY-SA 2.0
Robin Stott, via Flickr // CC BY-SA 2.0

15 Facts About Rosalind Franklin

Robin Stott, via Flickr // CC BY-SA 2.0
Robin Stott, via Flickr // CC BY-SA 2.0

Today would have been the 98th birthday of English chemist Rosalind Franklin, a brilliant and dedicated scientist best known for the honor denied her: the 1962 Nobel Prize for discovering the structure of DNA. Here are 15 facts about her.

1. SHE KNEW HER CALLING EARLY, BUT HER FATHER RESISTED EDUCATING A DAUGHTER.

Rosalind Elsie Franklin was born in London in 1920. She was one of five children born into a wealthy Jewish family. She decided she wanted to become a scientist at 15, and passed the admissions exam for Cambridge University. However, her father, Ellis, a merchant banker, objected to women going to college and refused to pay her tuition. Her aunt and mother finally managed to change his mind, and she enrolled at Cambridge's all-female Newnham College in 1938.

2. SHE ATTENDED COLLEGE WITH ANOTHER WOMAN WHO DIDN'T GET FULL CREDIT FOR HER WORK.

Bletchley Park cryptanalyst Joan Clarke was a few years older than Franklin, but they were both at Newnham in the late 1930s. Clarke would go on to be recruited for the war effort, cracking the German Enigma codes. The full scope of Clarke's work is still unknown, due to government secrecy.

3. HER SCHOLASTIC ACHIEVEMENTS WERE DENIED BY HER UNIVERSITY FOR YEARS.

Newnham College, Cambridge
Azeira, Wikimedia Commons // Public Domain

Despite Newnham College having been at Cambridge since 1871, the university refused to accept women as full members until 1948, seven years after Franklin earned the title of a degree in chemistry. Oxford University started granting women's degrees in 1920.

4. HER RESEARCH ON COAL HELPED THE AEROSPACE INDUSTRY.

After graduation, Franklin got a job at the British Coal Utilization Research Association (BCURA), where she researched coal and charcoal, and how it could be used for more than fuel. Her research formed the basis for her 1945 doctoral dissertation; it and several of her later papers on the micro-structures of carbon fibers played a role in the eventual use of carbon composites in air- and spacecraft construction.

5. HER MALE COLLEAGUES WERE HOSTILE AND UNDERMINED HER RESEARCH.

Franklin had a direct nature and was unwilling to be traditionally feminine. One reason she left Cambridge to work on coal was that her doctoral supervisor did not like her and believed women would always be less than men. When she was hired in 1951 at King's College, London, to work on DNA, she clashed with researcher Maurice Wilkins, who had thought she was his assistant, not his equal. Meanwhile, Franklin was under the impression that she'd be completely independent. Their relationship got worse and worse the longer they worked together. Wilkins went so far as to share Franklin's research without telling her with James Watson and Francis Crick—even though they were technically his competitors, funded by Cambridge University. Watson was particularly nasty about Franklin in his 1968 book, The Double Helix, criticizing her appearance and saying she had to be “put in her place.”

6. HOW EVENTS UNFOLDED IN THE DISCOVERY OF DNA'S STRUCTURE IS STILL DEBATED TODAY.

Double helix of DNA
Altayb, iStock

Many books have been written hashing over events, either criticizing Watson and Crick, saying they stole Franklin's research, or defending the duo, saying her research helped them but that Franklin would not ultimately have reached their conclusions on her own. Though Franklin and Watson never became friendly, Crick and his wife welcomed Franklin into their home while she was being treated for ovarian cancer.

7. HER WORK MAY HAVE LED TO HER UNTIMELY DEATH.

Franklin died of cancer in 1958. She was 37. Though genetics likely played a part in her illness, her work with crystal x-ray diffraction, which involved constant exposure to radiation, did not help. She is not the first woman in science to risk her health for her research. Marie Curie died from aplastic anemia, which has been tied to radiation exposure. Many of Curie's personal belongings, including her cookbooks, are too radioactive to handle even today.

8. HAD SHE LIVED LONGER, SHE MAY HAVE QUALIFIED FOR MORE THAN ONE NOBEL PRIZE.


Maurice Wilkins (on left), Francis Crick (third from left), and James Watson (fifth from left) accept their Nobel Prize in 1962.
Keystone, Getty Images

The first, of course, would have been awarded with Watson, Crick, and Wilkins, had they been made to share credit with her. (Pierre Curie had to ask the Nobel Committee to add his wife to the nomination in 1903.) As for the second, chemist Aaron Klug won the prize in 1982, carrying on work he and Franklin had started on viruses in 1953, after she left King's College. Because of the rules at the time of her death about awarding prizes posthumously (and in 1974 all posthumous awards were eliminated, the sole exception being in 2011), Franklin has none.

9. DESPITE BEING DENIED HER PRIZE, SHE'S BEEN HONORED BY MANY ACADEMICS.

In 2004, the Chicago Medical School renamed itself the Rosalind Franklin University of Medicine and Science. She has also had a number of academic programs, auditoriums, and labs named for her. In 2013, Newnham College principal Dame Carol Black helped install a plaque commemorating Franklin at the Eagle Pub in Cambridge. Crick and Watson, who already had a plaque in the pub, drank there often while working on the DNA project, and allegedly boasted about discovering “the secret of life” to other patrons.

10. SHE IS THE SUBJECT OF SEVERAL BIOGRAPHIES.

The first, 1975's Rosalind Franklin and DNA, was written by her friend Anne Sayre, largely as a reaction to Watson's The Double Helix. In 2002, Brenda Maddox published Rosalind Franklin: The Dark Lady of DNA.

11. AN OBJECT IN SPACE IS NAMED AFTER HER.

In 1997, amateur Australian astronomer John Broughton discovered an asteroid, which he named 9241 Rosfranklin.

12. AT LEAST ONE HISTORY RAP BATTLE IS ABOUT HER.

It was produced by seventh graders in Oakland, California (with some help from teacher Tom McFadden). And it is delightful.

13. SHE HAS BEEN IMMORTALIZED ON THE SMALL SCREEN AND THE BIG STAGE.

In 1987, BBC's Horizon series aired The Race for the Double Helix, starring Juliet Stevenson as Franklin. Jeff Goldblum played Watson. In 2011, playwright Anna Ziegler premiered a one-act about Franklin called Photograph 51. It opened on the West End in 2015, starring Nicole Kidman as Franklin.

14. THE 2015 RUN OF PHOTOGRAPH 51 RE-IGNITED THE OLD CONTROVERSY.

While Kidman got much praise from critics for her turn as Franklin in Photograph 51, Maurice Wilkins' friends and former colleagues have taken exception to a scene where Wilkins takes a photograph—the titular Photo 51, which showed evidence of DNA's structure—from Franklin's desk when she isn't there, saying he would never have done something so dishonorable.

15. THE PLAY MAY COME TO THE BIG SCREEN IN THE NEXT FEW YEARS.

In 2016, the West End production's director, Michael Grandage, told The Hollywood Reporter that he hopes to turn the play into a film—with Kidman reprising the role.

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Whale Sharks Can Live for More Than a Century, Study Finds
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iStock

Some whale sharks alive today have been swimming around since the Gilded Age. The animals—the largest fish in the ocean—can live as long as 130 years, according to a new study in the journal Marine and Freshwater Research. To give you an idea of how long that is, in 1888, Grover Cleveland was finishing up his first presidential term, Thomas Edison had just started selling his first light bulbs, and the U.S. only had 38 states.

To determine whale sharks' longevity, researchers from the Nova Southeastern University in Florida and the Maldives Whale Shark Research Program tracked male sharks around South Ari Atoll in the Maldives over the course of 10 years, calculating their sizes as they came back to the area over and over again. The scientists identified sharks that returned to the atoll every few years by their distinctive spot patterns, estimating their body lengths with lasers, tape, and visually to try to get the most accurate idea of their sizes.

Using these measurements and data on whale shark growth patterns, the researchers were able to determine that male whale sharks tend to reach maturity around 25 years old and live until they’re about 130 years old. During those decades, they reach an average length of 61.7 feet—about as long as a bowling lane.

While whale sharks are known as gentle giants, they’re difficult to study, and scientists still don’t know a ton about them. They’re considered endangered, making any information we can gather about them important. And this is the first time scientists have been able to accurately measure live, swimming whale sharks.

“Up to now, such aging and growth research has required obtaining vertebrae from dead whale sharks and counting growth rings, analogous to counting tree rings, to determine age,” first author Cameron Perry said in a press statement. ”Our work shows that we can obtain age and growth information without relying on dead sharks captured in fisheries. That is a big deal.”

Though whale sharks appear to be quite long-lived, their lifespan is short compared to the Greenland shark's—in 2016, researchers reported they may live for 400 years. 

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Scientists Find a Possible Link Between Beef Jerky and Mania
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iStock

Scientist have discovered a surprising new factor that may contribute to mania: meat sticks. As NBC News reports, processed meats containing nitrates, like jerky and some cold cuts, may provoke symptoms of mental illness.

For a new study, published in the journal Molecular Psychiatry, scientists surveyed roughly 1100 people with psychiatric disorders who were admitted into the Sheppard Pratt Health System in Baltimore between 2007 and 2017. They had initially set out to find whether there was any connection between certain infectious diseases and mania, a common symptom of bipolar disorder that can include racing thoughts, intense euphoria, and irritability.

While questioning participants about their diet, the researchers discovered that a significant number of them had eaten cured meats before their manic episodes. Patients who had recently consumed products like salami, jerky, and dried meat sticks were more likely to be hospitalized for mania than subjects in the control group.

The link can be narrowed down to nitrates, which are preservatives added to many types of cured meats. In a later part of the study, rats that were fed nitrate-free jerky acted less hyperactive than those who were given meat with nitrates.

Numerous studies have been published on the risks of consuming foods pumped full of nitrates: The ingredient can lead to the formation of carcinogens, and it can react in the gut in a way that promotes inflammation. It's possible that inflammation from nitrates can trigger mania in people who are already susceptible to it, but scientists aren't sure how this process might work. More research still needs to be done on the relationship between gut health and mental health before people with psychiatric disorders are told to avoid beef jerky altogether.

[h/t NBC News]

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